Services
Research and Clinical Development
Regulatory
Clinical
Biometrics
CMC
Consulting
Management Consulting
Market Access
Patient Engagement
Transaction Advisory
Lifecycle Optimization
Lifecycle Optimization
Real-World Solutions
Real-World Solutions
Biotech
Biotech
Technology
Clini-Sight
A virtual site addition that enables faster, more diverse, and more efficient clinical studies.
Evi-Sight
A digital Real-World Evidence (RWE) platform that collects and curates data that offers insight into the patient experience, clinical outcomes, patient behavior, and decision-making.
Care-Sight
A digital platform for Patient Support Programs (PSPs) and digital therapeutics (DTx).
Health Storylines
A patient-driven digital operating system that covers multiple use-cases from decentralized clinical trials (DCT) to Real-World Evidence (RWE) generation, and patient support programs.
About
Meet Our Team
Our team collaborates to fully understand every aspect of each client’s organization from concept ideation to commercial realization, from innovation to implementation
Community Involvement
We work with our local and global communities to create positive change through education, service, and sustainable business practices
800+
employees
90+%
has a PhD and/or Masters
15
languages spoken
30
nationalities
Careers
Resources
News
Read all the latest from us
Blog
Gain insights on healthcare innovation and more
Publications
Discover our latest industry infographics, articles, white papers, and more
Multimedia
Visit our videos, podcasts, webinars, and more
Case Studies
Learn how we deliver meaningful results for clients
Latest in the hub
How to Accelerate Lupus Solutions with RWD
Published: November, 2023
SOHONOS, the First Drug for Fibrodysplasia Ossificans Progressiva, Receives US FDA Approval with Real-World Evidence as External Control
Published: November, 2023
Technological Innovations in Diabetes Management Medical Devices
Published: November, 2023
Services
Overview
Research and Clinical Development
Regulatory Clinical Biometrics CMC
Consulting
Management Consulting Market Access Patient Engagement Transaction Advisory Lifecycle Optimization
Real-World Solutions
Real-World Solutions
Biotech
Biotech
Technology
Overview Clini-Sight Evi-Sight Care-Sight Health Storylines
About
Overview Meet Our Team Community Involvement
Careers
Resources
Overview News Blog Publications Multimedia Case Studies
Home > Education Hub > Manufacturing Challenges of Therapeutic Antibody-Drug Conjugates

Manufacturing Challenges of Therapeutic Antibody-Drug Conjugates

Antibody drug conjugates (ADCs) make up an important new modality that shows great results in treating certain types of cancer. Manufacturing this drug class is complex because it requires several Good Manufacturing Practices (GMP) intermediates as inputs to the conjugation reaction to produce the drug substance.

Our expert Chemistry, Manufacturing, and Controls (CMC) team conducted a detailed technical review to address the manufacturing challenges of ADCs. Read “Manufacturing Challenges of Therapeutic Antibody-Drug Conjugates” in the latest issue of BioProcess International (September 2023).

Publications
Category:
CMC Drug Development
Published on:
September 20, 2023
Read the article now

Our experts behind the article “Manufacturing Challenges of Therapeutic Antibody-Drug Conjugates”:

  • Peter Alexander
  • Kelly Weitzel
  • Angela Linderholm
  • William E. Haskins
  • Sanjeevani Ghone
  • Steven M. Chamow

Contact us to discover how our team’s comprehensive knowledge in biologics and ADCs can make a significant difference in your development journey.

Welcome to Alira Health. This site is best viewed in Chrome, Microsoft Edge, or Firefox.