Steven Chamow, PhD
Steven Chamow, PhD, is Alira Health’s Senior Vice President of CMC Development. He is an experienced biotechnology executive and consultant, with more than 35 years of biopharmaceutical experience. As principal consultant, Dr. Chamow draws on his extensive technical and product development background to assist biotechnology companies in designing and developing CMC strategies for products in development, including transfer to and implementation by qualified CDMOs.
Prior to founding Chamow & Associates, Dr. Chamow served as senior vice president, CMC at Intradigm Corporation, a private biopharmaceutical company focused on developing RNAi therapeutics (acquired by Silence Therapeutics). Prior to Intradigm, Dr. Chamow was vice president, process sciences, at Genitope Corporation and at Abgenix, Inc. (acquired by Amgen), where he built the company’s process sciences department and co-led the design and construction of Abgenix’s award-winning mammalian-cell production facility in Fremont, CA. Prior to Abgenix, Dr. Chamow served as director of biopharmaceutical development at Scios, Inc., (acquired by Johnson & Johnson), and as a scientist and senior scientist in process development at Genentech.
Dr. Chamow was educated at the University of California, earning a B.A. in biology from UC Santa Cruz and a PhD in biochemistry from UC Davis. He completed his postdoctoral training at the National Institutes of Health. Dr. Chamow is an inventor on twelve issued patents and has contributed to the development of three marketed products (Avastin®, Natrecor®, Vectibix®, Zadaxin®). He has co-authored over 50 publications in peer-reviewed journals and co-edited two books: “Antibody Fusion Proteins” and “Therapeutic Fc Fusion Proteins.”
Key areas of expertise
- Monoclonal Antibodies and Derivatives
- Characterization and Analysis of Biologics
- Recombinant Glycoprotein Production
- Scale Up and GMP Manufacture of Biologics